Rabbit anti-Human DLGAP4 Polyclonal Antibody | anti-Dlgap4 antibody

DLGAP4, NT (DLGAP4, DAP4, KIAA0964, SAPAP4, Disks large-associated protein 4, PSD-95/SAP90-binding protein 4, SAP90/PSD-95-associated protein 4)

Cat. Num. AAA648319

• Gene Names: Dlgap4; DAP4; DAP-4; WBP16; Sapap4; SAPAP-4; AI225853; BC024558
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: DLGAP4; Polyclonal Antibody; NT (DLGAP4; DAP4; KIAA0964; SAPAP4; Disks large-associated protein 4; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4); Anti -DLGAP4; anti-Dlgap4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-Dlgap4 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: DLGAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human DLGAP4.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(DLGAP4 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the DLGAP4 antibody detected the DLGAP4 protein (arrow).)

Related Product Information for anti-Dlgap4 antibody

DLGAP4 is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-Dlgap4 antibody

Antibodies; Abs to Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 219841800
• NCBI GeneID: 228836
• UniProt Accession #: B1AZP2; Q3KQQ8; Q6PD44; Q6XBF1; Q80TN3; Q8R3U9; B1AZP3; B7ZNS1
• Molecular Weight: 108,037 Da
• NCBI Official Full Name: Dlgap4 protein
• NCBI Official Synonym Full Names: discs, large homolog-associated protein 4 (Drosophila)
• NCBI Official Symbol: Dlgap4
• NCBI Official Synonym Symbols: DAP4; DAP-4; WBP16; Sapap4; SAPAP-4; AI225853; BC024558
• NCBI Protein Information: disks large-associated protein 4; WW domain-binding protein 16; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4
• UniProt Protein Name: Disks large-associated protein 4
• Protein Family: Disks large-associated protein
• UniProt Gene Name: Dlgap4
• UniProt Synonym Gene Names: Kiaa0964; Sapap4; DAP-4; SAPAP-4
• UniProt Entry Name: DLGP4_MOUSE

NCBI Description

This gene encodes a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. The encoded protein may play a role in synapse organization and neuronal signalling. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

Uniprot Description

Function: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane

By similarity.

Subunit structure: Interacts with DLG1 and DLG4/PSD-95

By similarity.

Subcellular location: Membrane; Peripheral membrane protein

By similarity.

Sequence similarities: Belongs to the SAPAP family.

Sequence caution: The sequence BAC65690.2 differs from that shown. Reason: Intron retention.