Testing Data
Rabbit DGAT1 Polyclonal Antibody | anti-DGAT1 antibody
DGAT1 Antibody
Appearance: Colorless liquid
Shelf Life: 12 months
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
DGAT1: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; EC 2.3.1.20; Transferase; Lipid Metabolism - glycerolipid; EC 2.3.1.76; Membrane protein, multi-pass
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: 2-acylglycerol O-acyltransferase activity; transferase activity; diacylglycerol binding; transferase activity, transferring acyl groups; O-acyltransferase activity; retinol O-fatty-acyltransferase activity; fatty acid binding; diacylglycerol O-acyltransferase activity
Biological Process: sequestering of lipid; insulin secretion; fatty acid homeostasis; glycerolipid metabolic process; triacylglycerol biosynthetic process; diacylglycerol metabolic process
Research Articles on DGAT1
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Product Notes
The DGAT1 dgat1 (Catalog #AAA841302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DGAT1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DGAT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60 kDa DGAT-1 of human, mouse, and rat origins. Reactivity to other species has not been tested. Researchers should empirically determine the suitability of the DGAT1 dgat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DGAT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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