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Rabbit DENND1A Polyclonal Antibody | anti-DENND1A antibody

DENND1A

Gene Names
DENND1A; FAM31A; KIAA1608
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
DENND1A; Polyclonal Antibody; Purified Rabbit Anti Human DENND1A Polyclonal antibody; FAM31A; KIAA1608; anti-DENND1A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2019
Applicable Applications for anti-DENND1A antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 233aa-414aa of human DENND1A.
Cellular Localization
Cell Junction, Cell Membrane, Cytoplasmic Vesicle, Membrane and Synapse
Related Product Information for anti-DENND1A antibody
Homo sapiens DENN/MADD domain containing 1A, mRNA
References
Nagase T, Ishikawa K, Nakajima D. et al. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Research. 5 (1):169 (1998)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
100KD
NCBI Official Full Name
Homo sapiens DENN/MADD domain containing 1A, mRNA
NCBI Official Synonym Full Names
DENN domain containing 1A
NCBI Official Symbol
DENND1A
NCBI Official Synonym Symbols
FAM31A; KIAA1608
NCBI Protein Information
DENN domain-containing protein 1A

NCBI Description

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

Research Articles on DENND1A

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Product Notes

The DENND1A (Catalog #AAA8563023) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DENND1A reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DENND1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-80000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the DENND1A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DENND1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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