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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/25,)

Rabbit anti-Human DEK Polyclonal Antibody | anti-DEK antibody

DEK Antibody

Gene Names
DEK; D6S231E
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
DEK; Polyclonal Antibody; DEK Antibody; D6S231E; anti-DEK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total DEK protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.7 mg/ml (varies by lot)
Sequence Length
341
Applicable Applications for anti-DEK antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen
Synthetic peptide of human DEK
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/25,)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/25,)
Related Product Information for anti-DEK antibody
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoformshave been found for this gene.
Product Categories/Family for anti-DEK antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,705 Da
NCBI Official Full Name
protein DEK isoform 2
NCBI Official Synonym Full Names
DEK proto-oncogene
NCBI Official Symbol
DEK
NCBI Official Synonym Symbols
D6S231E
NCBI Protein Information
protein DEK
UniProt Protein Name
Protein DEK
Protein Family
UniProt Gene Name
DEK
UniProt Entry Name
DEK_HUMAN

Uniprot Description

DEK: a ubiquitous protein with a SAP domain, which is found in a variety of nuclear proteins involved in transcription, DNA repair, RNA processing or apoptotic chromatin degradation. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemias (AML).

Protein type: DNA replication; DNA-binding; Histone-binding; Oncoprotein; RNA splicing

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: chromatin binding; histone binding

Biological Process: chromatin remodeling; positive regulation of gene expression, epigenetic; regulation of transcription from RNA polymerase II promoter; signal transduction; transcription from RNA polymerase II promoter; viral genome replication

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Product Notes

The DEK dek (Catalog #AAA9415799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DEK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEK can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the DEK dek for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DEK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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