Western Blot (WB)
(DEGS2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).)
Rabbit anti-Human DEGS2 Polyclonal Antibody | anti-DEGS2 antibody
DEGS2, CT (DEGS2, C14orf66, Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2, Degenerative spermatocyte homolog 2) (AP)
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(DEGS2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).)
Western Blot (WB)
(DEGS2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).)
Immunohistochemistry (IHC)
(DEGS2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEGS2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(DEGS2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEGS2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008]
Uniprot Description
Function: Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase
By similarity. UniProtKB Q8R2F2
Pathway: Membrane lipid metabolism; sphingolipid biosynthesis.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity UniProtKB Q8R2F2.
Tissue specificity: Highly expressed in skin, intestine and kidney. Ref.1
Induction: Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Ref.1
Sequence similarities: Belongs to the fatty acid desaturase family. DEGS subfamily.
Research Articles on DEGS2
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Product Notes
The DEGS2 degs2 (Catalog #AAA6291651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DEGS2, CT (DEGS2, C14orf66, Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2, Degenerative spermatocyte homolog 2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEGS2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-100 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DEGS2 degs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DEGS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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