Rabbit anti-Human DECR1 Polyclonal Antibody | anti-DECR1 antibody

DECR1 antibody

Cat. Num. AAA9410544

• Gene Names: DECR1; DECR; NADPH; SDR18C1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: DECR1; Polyclonal Antibody; DECR1 antibody; anti-DECR1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 335

• Applicable Applications for anti-DECR1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500-1:3000; Immunohistochemistry: 1:50-1:500; Immunofluorescence: 1:100-1:200
• Immunogen Type: Recombinant protein
• Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 305 of DECR1
• Target Name: DECR1
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE Primary antibody diluted at 1: 10000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using DECR1 antibody at 1: 500 dilution.)

Immunofluorescence (IF)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using DECR1 antibody at 1: 200 dilution.)

Related Product Information for anti-DECR1 antibody

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq]

Product Categories/Family for anti-DECR1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 4503301
• NCBI GeneID: 1666
• NCBI Accession #: NP_001350
• NCBI GenBank Nucleotide #: NM_001359.1
• Molecular Weight: 34,994 Da
• NCBI Official Full Name: 2,4-dienoyl-CoA reductase, mitochondrial
• NCBI Official Synonym Full Names: 2,4-dienoyl CoA reductase 1, mitochondrial
• NCBI Official Symbol: DECR1
• NCBI Official Synonym Symbols: DECR; NADPH; SDR18C1
• NCBI Protein Information: 2,4-dienoyl-CoA reductase, mitochondrial
• UniProt Protein Name: 2,4-dienoyl-CoA reductase, mitochondrial
• Protein Family: 2,4-dienoyl-CoA reductase
• UniProt Gene Name: DECR1
• UniProt Synonym Gene Names: DECR; SDR18C1; 4-enoyl-CoA reductase [NADPH]
• UniProt Entry Name: DECR_HUMAN

NCBI Description

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

Uniprot Description

DECR1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.

Protein type: Mitochondrial; EC 1.3.1.34; Oxidoreductase

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; nucleus

Molecular Function: oxidoreductase activity, acting on NADH or NADPH; 2,4-dienoyl-CoA reductase (NADPH) activity

Biological Process: fatty acid beta-oxidation; cellular lipid metabolic process; protein homotetramerization