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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gliomas using MBS768510 (DCUN1D1 antibody) at dilution of 1:50)

Rabbit DCUN1D1 Polyclonal Antibody | anti-DCUN1D1 antibody

DCUN1D1 Rabbit Polyclonal

Gene Names
DCUN1D1; RP42; SCRO; Tes3; DCNL1; SCCRO; DCUN1L1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
DCUN1D1; Polyclonal Antibody; DCUN1D1 Rabbit Polyclonal; anti-DCUN1D1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
244
Applicable Applications for anti-DCUN1D1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gliomas using MBS768510 (DCUN1D1 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gliomas using MBS768510 (DCUN1D1 antibody) at dilution of 1:50)

Western Blot (WB)

(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS768510 (DCUN1D1 Antibody) at dilution of 1:3000)

Western Blot (WB) (Jurkat cells were subjected to SDS PAGE followed by western blot with MBS768510 (DCUN1D1 Antibody) at dilution of 1:3000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,124 Da
NCBI Official Full Name
DCN1-like protein 1 isoform 2
NCBI Official Synonym Full Names
defective in cullin neddylation 1 domain containing 1
NCBI Official Symbol
DCUN1D1
NCBI Official Synonym Symbols
RP42; SCRO; Tes3; DCNL1; SCCRO; DCUN1L1
NCBI Protein Information
DCN1-like protein 1
UniProt Protein Name
DCN1-like protein 1
Protein Family
UniProt Gene Name
DCUN1D1
UniProt Synonym Gene Names
DCUN1L1; RP42; SCCRO
UniProt Entry Name
DCNL1_HUMAN

Uniprot Description

DCUN1D1: Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.

Protein type: Oncoprotein; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 3q26.3

Cellular Component: nucleus; ubiquitin ligase complex

Molecular Function: protein binding; small conjugating protein binding; ubiquitin conjugating enzyme binding

Biological Process: positive regulation of ubiquitin-protein ligase activity; protein neddylation

Research Articles on DCUN1D1

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Product Notes

The DCUN1D1 dcun1d1 (Catalog #AAA768510) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DCUN1D1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DCUN1D1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the DCUN1D1 dcun1d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCUN1D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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