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Western Blot (WB) (Western blot analysis of anti-CYP1A1 Antibody (Center) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human, Mouse CYP1A1 Polyclonal Antibody | anti-CYP1A1 antibody

CYP1A1, CT (Cytochrome P450 1A1, Cytochrome P450-P1, Cytochrome P450 Form 6, Cytochrome P450-C) (MaxLight 750)

Gene Names
CYP1A1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
CYP1A1; Polyclonal Antibody; CT (Cytochrome P450 1A1; Cytochrome P450-P1; Cytochrome P450 Form 6; Cytochrome P450-C) (MaxLight 750); anti-CYP1A1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CYP1A1. Species Crossreactivity: mouse.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Applicable Applications for anti-CYP1A1 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the center region of human CYP1A1 (KLH).
Conjugate
MaxLight750
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-CYP1A1 Antibody (Center) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-CYP1A1 Antibody (Center) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of CYP1A1 Antibody (Center) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).)

Immunofluorescence (IF) (Confocal immunofluorescent analysis of CYP1A1 Antibody (Center) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).)

Immunohistochemistry (IHC)

(CYP1A1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP1A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (CYP1A1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP1A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-CYP1A1 antibody
References
1. Delpisheh, A., Eur. J. Obstet. Gynecol. Reprod. Biol. 143(1), 38-42 (2009). 2. Zhuo, W., Cancer Invest. 27(1), 86-95 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,441 Da
NCBI Official Full Name
cytochrome P450 1A1
NCBI Official Synonym Full Names
cytochrome P450, family 1, subfamily A, polypeptide 1
NCBI Official Symbol
CYP1A1
NCBI Official Synonym Symbols
AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
NCBI Protein Information
cytochrome P450 1A1
Protein Family

NCBI Description

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]

Research Articles on CYP1A1

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Product Notes

The CYP1A1 (Catalog #AAA6471522) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP1A1, CT (Cytochrome P450 1A1, Cytochrome P450-P1, Cytochrome P450 Form 6, Cytochrome P450-C) (MaxLight 750) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CYP1A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CYP1A1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP1A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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