Western Blot (WB)
(CCND3 rabbit polyclonal antibody. Western Blot analysis of CCND3 expression in Jurkat.)
Rabbit anti-Human Cyclin D3 Polyclonal Antibody | anti-CCND3 antibody
Cyclin D3 (G1/S-specific Cyclin-D3, CCND3) (HRP)
Western Blot (WB)
(CCND3 rabbit polyclonal antibody. Western Blot analysis of CCND3 expression in Jurkat.)
Western Blot (WB)
(CCND3 rabbit polyclonal antibody. Western Blot analysis of CCND3 expression in Jurkat.)
Western Blot (WB)
(Western Blot analysis of CCND3 expression in transfected 293T cell line by CCND3 polyclonal antibody. Lane 1: CCND3 transfected lysate (32.5kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CCND3 expression in transfected 293T cell line by CCND3 polyclonal antibody. Lane 1: CCND3 transfected lysate (32.5kD). Lane 2: Non-transfected lysate.)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between CCND3 and AREG. HeLa cells were stained with CCND3 rabbit purified polyclonal 1:1200 and AREG mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between CCND3 and AREG. HeLa cells were stained with CCND3 rabbit purified polyclonal 1:1200 and AREG mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Research Articles on CCND3
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Product Notes
The CCND3 (Catalog #AAA6375307) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cyclin D3 (G1/S-specific Cyclin-D3, CCND3) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cyclin D3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CCND3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclin D3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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