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Immunohistochemistry - Paraffin (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human CYC1 / Cytochrome C-1 Polyclonal Antibody | anti-CYC1 antibody

Anti-CYC1 / Cytochrome C-1 Antibody IHC-plus

Gene Names
CYC1; UQCR4; MC3DN6
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Caprylic acid and ammonium sulfate precipitation
Synonyms
CYC1 / Cytochrome C-1; Polyclonal Antibody; Anti-CYC1 / Cytochrome C-1 Antibody IHC-plus; Rabbit Polyclonal (IgG) to Human CYC1 / Cytochrome C-1; Human CYC1 / Cytochrome C-1; Complex III subunit 4; Cytochrome c-1; UQCR4; Complex III subunit IV; anti-CYC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human CYC1 / Cytochrome C-1
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Sequence Length
325
Applicable Applications for anti-CYC1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
IHC-P (10 ug/ml)
Immunogen
CYC1 / Cytochrome C-1 antibody was raised against recombinant human Cytochrome c1, heme protein, mitochondrial protein.
Immunogen Description
Recombinant human Cytochrome c1, heme protein, mitochondrial protein.
Immunogen Type
Recombinant protein
Target Species
Human
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.

Immunohistochemistry - Paraffin (IHC)

(Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC)

(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot of Cytochrome c1, heme protein, mitochondrial Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.)

Western Blot (WB) (Western blot of Cytochrome c1, heme protein, mitochondrial Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.)
Related Product Information for anti-CYC1 antibody
CYC1 Antibody, Complex III subunit 4 Antibody, Cytochrome c-1 Antibody, UQCR4 Antibody, Complex III subunit IV Antibody Description: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,422 Da
NCBI Official Full Name
cytochrome c1, heme protein, mitochondrial
NCBI Official Synonym Full Names
cytochrome c1
NCBI Official Symbol
CYC1
NCBI Official Synonym Symbols
UQCR4; MC3DN6
NCBI Protein Information
cytochrome c1, heme protein, mitochondrial
UniProt Protein Name
Cytochrome c1, heme protein, mitochondrial
Protein Family
UniProt Gene Name
CYC1
UniProt Synonym Gene Names
Cytochrome c-1
UniProt Entry Name
CY1_HUMAN

NCBI Description

This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]

Uniprot Description

CYC1: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family.

Protein type: Oxidoreductase; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: integral to membrane; membrane; mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; heme binding; metal ion binding

Biological Process: cellular metabolic process; response to glucagon stimulus

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 6

Research Articles on CYC1

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Product Notes

The CYC1 cyc1 (Catalog #AAA249999) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CYC1 / Cytochrome C-1 Antibody IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYC1 / Cytochrome C-1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). IHC-P (10 ug/ml). Researchers should empirically determine the suitability of the CYC1 cyc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYC1 / Cytochrome C-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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