Testing Data
Rabbit CYB5R4 Polyclonal Antibody | anti-CYB5R4 antibody
CYB5R4 Antibody
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010]
Uniprot Description
CYB5R4: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein type: Oxidoreductase; EC 1.6.2.2; Endoplasmic reticulum; Cell development/differentiation
Chromosomal Location of Human Ortholog: 6pter-q22.33
Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum
Molecular Function: FAD binding; NADPH-hemoprotein reductase activity; NAD(P)H oxidase activity; cytochrome-b5 reductase activity; metal ion binding; oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor; heme binding
Biological Process: response to antibiotic; generation of precursor metabolites and energy; detection of oxygen; insulin secretion; superoxide metabolic process; glucose homeostasis; NADP metabolic process; cell development
Research Articles on CYB5R4
Similar Products
Product Notes
The CYB5R4 cyb5r4 (Catalog #AAA2525110) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYB5R4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CYB5R4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:5000. Researchers should empirically determine the suitability of the CYB5R4 cyb5r4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYB5R4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
