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Western Blot (WB) (Western blot analysis of extracts from COS-7 cells and COLO205 cells, using Mevalonate Kinase antibody.)

anti-Human Mevalonate Kinase Antibody | anti-MVK antibody

Mevalonate Kinase Antibody

Gene Names
MVK; MK; LRBP; MVLK; POROK3
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
Mevalonate Kinase; Mevalonate Kinase Antibody; Mevalonate kinase; EC 2.7.1.36; MK; anti-MVK antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
Mevalonate Kinase Antibody detects endogenous levels of total Mevalonate Kinase
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
396
Applicable Applications for anti-MVK antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from COS-7 cells and COLO205 cells, using Mevalonate Kinase antibody.)

Western Blot (WB) (Western blot analysis of extracts from COS-7 cells and COLO205 cells, using Mevalonate Kinase antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42 KD
NCBI Official Full Name
mevalonate kinase isoform a
NCBI Official Synonym Full Names
mevalonate kinase
NCBI Official Symbol
MVK
NCBI Official Synonym Symbols
MK; LRBP; MVLK; POROK3
NCBI Protein Information
mevalonate kinase
UniProt Protein Name
Mevalonate kinase
Protein Family
UniProt Gene Name
MVK
UniProt Synonym Gene Names
MK

NCBI Description

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

May be a regulatory site in cholesterol biosynthetic pathway.

Research Articles on MVK

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Product Notes

The MVK mvk (Catalog #AAA8513976) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Mevalonate Kinase Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mevalonate Kinase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MVK mvk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mevalonate Kinase, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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