Rabbit anti-Mouse, Rat CXCR3 Polyclonal Antibody | anti-CXCR3 antibody
CXCR3 Antibody BIOTIN-Conjugated
Confocal Microscopy: 1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Immunocytochemistry: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500
NCBI and Uniprot Product Information
NCBI Description
binds interferon-inducible protein-10 and induces intracellular calcium mobilization; increased expression occurs in response to focal stroke [RGD, Feb 2006]
Uniprot Description
CXCR3: Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC). Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Cellular Component: cell surface; external side of plasma membrane; integral to membrane; intracellular; plasma membrane
Molecular Function: C-X-C chemokine binding; C-X-C chemokine receptor activity; chemokine binding; receptor activity
Biological Process: angiogenesis; calcium-mediated signaling; cell surface receptor linked signal transduction; chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; inflammatory response; negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; positive regulation of angiogenesis; positive regulation of cAMP metabolic process; positive regulation of cell proliferation; positive regulation of chemotaxis; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of transcription from RNA polymerase II promoter; regulation of leukocyte migration
Research Articles on CXCR3
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Product Notes
The CXCR3 cxcr3 (Catalog #AAA541349) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CXCR3 Antibody BIOTIN-Conjugated reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CXCR3 can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunology (IMM), Western Blot (WB). Recommended Dilutions: Confocal Microscopy: 1:200 Dot Blot: 1:10,000 ELISA: 1:10,000 Immunoprecipitation: 1:200 Immunocytochemistry: 1:200 Immunohistochemistry: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the CXCR3 cxcr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXCR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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