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Western Blot (WB) (CU002 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CU002 antibody detected the CU002 protein (arrow).)

Rabbit anti-Human CU002 Polyclonal Antibody | anti-C21orf2 antibody

CU002 Antibody (C-term)

Gene Names
C21orf2; LRRC76; YF5/A2
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CU002; Polyclonal Antibody; CU002 Antibody (C-term); Protein C21orf2; C21orf-HUMF09G85; YF5/A2; C21orf2; anti-C21orf2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CU002 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the C-terminal region of human CU002.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
169-198
Sequence Length
375
Applicable Applications for anti-C21orf2 antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(CU002 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CU002 antibody detected the CU002 protein (arrow).)

Western Blot (WB) (CU002 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CU002 antibody detected the CU002 protein (arrow).)

Flow Cytometry (FC/FACS)

(CU002 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (CU002 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-C21orf2 antibody
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Shim, K.S., et al. J. Neural Transm. Suppl. 67, 117-128 (2003) :
Scott, H.S., et al. Genomics 47(1):64-70(1998)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
755
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28340
NCBI Official Full Name
nuclear encoded mitochondrial protein C21orf2 isoform 2
NCBI Official Synonym Full Names
chromosome 21 open reading frame 2
NCBI Official Symbol
C21orf2
NCBI Official Synonym Symbols
LRRC76; YF5/A2
NCBI Protein Information
nuclear encoded mitochondrial protein C21orf2; protein C21orf2
UniProt Protein Name
Protein C21orf2
Protein Family
UniProt Gene Name
C21orf2
UniProt Entry Name
CU002_HUMAN

NCBI Description

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012]

Uniprot Description

C21orf2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytoplasm; plasma membrane

Biological Process: regulation of cell shape; smoothened signaling pathway; cytoskeleton organization and biogenesis

Research Articles on C21orf2

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Product Notes

The C21orf2 c21orf2 (Catalog #AAA9207617) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 169-198. The CU002 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CU002 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the C21orf2 c21orf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CU002, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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