Uncharacterized protein C21orf2 (C21orf2) Recombinant Protein | C21orf2 recombinant protein
Recombinant Human Uncharacterized protein C21orf2 (C21orf2)
NCBI and Uniprot Product Information
NCBI Description
Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012]
Uniprot Description
C21orf2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: cytoplasm; plasma membrane
Biological Process: regulation of cell shape; smoothened signaling pathway; cytoskeleton organization and biogenesis
Research Articles on C21orf2
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Product Notes
The C21orf2 c21orf2 (Catalog #AAA1261288) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-375aa; Full Length. The amino acid sequence is listed below: MKLTRKMVLT RAKASELHSV RKLNCWGSRL TDISICQEMP SLEVITLSVN SISTLEPVSR CQRLSELYLR RNRIPSLAEL FYLKGLPRLR VLWLAENPCC GTSPHRYRMT VLRTLPRLQK LDNQAVTEEE LSRALSEGEE ITAAPEREGT GHGGPKLCCT LSSLSSAAET GRDPLDSEEE ATGAQDERGL KPPSRGQFPS LSARDASSSH RGRVSGGPLG AAAASAHCTH CTETVGREHG ASQGPVGREH GASQGLEELC PRGSCVCGSV NAHTRVTRAP HGAVLAPQPL LLSWSVECGP GPCWAEGNRS HVEEVPHTRP QAGLLCSDSP SVPNVLTAIL LLLRELDAEG LEAVQQTVGS RLQALRGEEV QEHAE. It is sometimes possible for the material contained within the vial of "Uncharacterized protein C21orf2 (C21orf2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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