Testing Data
FKBPL active protein
Human Recombinant FKBPL
Gene Names
FKBPL; NG7; DIR1; FKBP4; WISP39
Applications
SDS-Page
Purity
>=90%
Synonyms
FKBPL; Human Recombinant FKBPL; FK506 binding protein like; DIR1; NG7; WISP39.; FKBPL active protein
Host
E Coli
Purity/Purification
>=90%
Form/Format
0.25 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 1 mM EDTA and 100 mM NaCl.
Appearance: Liquid
Appearance: Liquid
Concentration
0.25 mg/ml (varies by lot)
Sequence
METPPVNTIG EKDTSQPQQE WEKNLRENLD SVIQIRQQPR DPPTETLELE VSPDPASQIL EHTQGAEKLV AELEGDSHKS HGSTSQMPEA LQASDLWYCP DGSFVKKIVI RGHGLDKPKL GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNPEGAA RCYGRALRLL LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG NLEKATADLK KVLAIDPKNR AAQEELGKVV IQGKNQDAGL AQGLRKMFGL EHHHHHH
Sequence Length
349
Applicable Applications for FKBPL active protein
SDS-PAGE
Biological Activity
Specific activity is > 210 nmoles/min/mg.
Unit Definition
Specific activity is defined as the amount of enzyme that cleaves 1 umole of suc-AAFP-pNA per minute at 25 degree C in Tris HCl pH 8.0 using chymotrypsin.
Handling
Centrifuge the vial prior to opening.
Preparation and Storage
At -80 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for FKBPL active protein
Background: FKBPL is related to the immunophilin protein family, which take part in immunoregulation and regular cellular processes involving protein folding and trafficking. FKBPL has an important function in the induced radio resistance and participates in the control of the cell cycle. FKBPL has a role in cellular response to stress. FKBPL interacts with Hsp90, glucocorticoid receptor and dynamitin and is involved in signaling, like other FKBPs.
Product Categories/Family for FKBPL active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39.2 kDa
NCBI Official Full Name
FK506-binding protein-like
NCBI Official Synonym Full Names
FK506 binding protein like
NCBI Official Symbol
FKBPL
NCBI Official Synonym Symbols
NG7; DIR1; FKBP4; WISP39
NCBI Protein Information
FK506-binding protein-like
UniProt Protein Name
FK506-binding protein-like
Protein Family
UniProt Gene Name
FKBPL
UniProt Synonym Gene Names
DIR1; NG7; WISp39
UniProt Entry Name
FKBPL_HUMAN
NCBI Description
The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]
Uniprot Description
FKBPL: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: endoplasmic reticulum membrane
Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; FK506 binding
Biological Process: response to radiation; protein peptidyl-prolyl isomerization
Research Articles on FKBPL
Similar Products
Product Notes
The FKBPL fkbpl (Catalog #AAA844870) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FKBPL can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the FKBPL fkbpl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: METPPVNTIG EKDTSQPQQE WEKNLRENLD SVIQIRQQPR DPPTETLELE VSPDPASQIL EHTQGAEKLV AELEGDSHKS HGSTSQMPEA LQASDLWYCP DGSFVKKIVI RGHGLDKPKL GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNPEGAA RCYGRALRLL LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG NLEKATADLK KVLAIDPKNR AAQEELGKVV IQGKNQDAGL AQGLRKMFGL EHHHHHH. It is sometimes possible for the material contained within the vial of "FKBPL, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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