Rabbit CTSO Polyclonal Antibody | anti-CTSO antibody

CTSO Polyclonal Antibody

Cat. Num. AAA3006899

• Gene Names: CTSO; CTSO1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: CTSO; Polyclonal Antibody; CTSO Polyclonal Antibody; Cathepsin O; CTSO1; anti-CTSO antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: CTSO polyclonal antibody detects endogenous levels of CTSO protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 321

• Applicable Applications for anti-CTSO antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human CTSO
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of CTSO polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264. 7 whole cell lysate Lane3:H9C2 whole cell lysate)

Related Product Information for anti-CTSO antibody

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.

NCBI and Uniprot Product Information

• NCBI GI #: 4557501
• NCBI GeneID: 1519
• NCBI Accession #: NP_001325
• NCBI GenBank Nucleotide #: NP_001325.1
• UniProt Accession #: P43234
• Molecular Weight: ~ 36kDa
• NCBI Official Full Name: cathepsin O preproprotein
• NCBI Official Synonym Full Names: cathepsin O
• NCBI Official Symbol: CTSO
• NCBI Official Synonym Symbols: CTSO1
• NCBI Protein Information: cathepsin O
• UniProt Protein Name: Cathepsin O
• Protein Family: Cathepsin
• UniProt Gene Name: CTSO
• UniProt Synonym Gene Names: CTSO1
• UniProt Entry Name: CATO_HUMAN

NCBI Description

The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]