Rabbit anti-Human CTSO Polyclonal Antibody | anti-CTSO antibody

CTSO, NT (CTSO, CTSO1, Cathepsin O) (AP)

Cat. Num. AAA6289935

• Gene Names: CTSO; CTSO1
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CTSO; Polyclonal Antibody; NT (CTSO; CTSO1; Cathepsin O) (AP); Cathepsin O; anti-CTSO antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-CTSO antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: CTSO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-106 amino acids from the N-terminal region of human CTSO.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CTSO Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CTSO antibody detected the CTSO protein (arrow).)

Immunohistochemistry (IHC)

(CTSO Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTSO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-CTSO antibody

The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase.

Product Categories/Family for anti-CTSO antibody

Antibodies; Cathepsin

References

Roeske, D., et al. Mol. Psychiatry (2009). In press: Lamesch, P., et al. Genomics 89(3):307-315(2007). Santamaria, I., et al. Genomics 53(2):231-234(1998). Shi, G.P., et al. FEBS Lett. 357(2):129-134(1995) Velasco, G., et al. J. Biol. Chem. 269(43):27136-27142(1994).

NCBI and Uniprot Product Information

• NCBI GI #: 4557501
• NCBI GeneID: 1519
• NCBI Accession #: NP_001325.1
• NCBI GenBank Nucleotide #: NM_001334.2
• UniProt Accession #: P43234
• Molecular Weight: 35,958 Da
• NCBI Official Full Name: cathepsin O preproprotein
• NCBI Official Synonym Full Names: cathepsin O
• NCBI Official Symbol: CTSO
• NCBI Official Synonym Symbols: CTSO1
• NCBI Protein Information: cathepsin O
• UniProt Protein Name: Cathepsin O
• Protein Family: Cathepsin
• UniProt Gene Name: CTSO
• UniProt Synonym Gene Names: CTSO1
• UniProt Entry Name: CATO_HUMAN

NCBI Description

The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]