Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 822164(CTNNBIP1 Antibody) at dilution 1/30. (Original magnification: ×200))
Rabbit anti-Human, Mouse CTNNBIP1/ICAT Polyclonal Antibody | anti-CTNNBIP1/ICAT antibody
CTNNBIP1/ICAT Rabbit pAb
IHC: 1:50-1:200
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 822164(CTNNBIP1 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 822164(CTNNBIP1 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 822164(CTNNBIP1 Antibody) at dilution 1/30. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 822164(CTNNBIP1 Antibody) at dilution 1/30. (Original magnification: ×200))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.
Protein type: Cell development/differentiation; Inhibitor
Chromosomal Location of Human Ortholog: 1p36.22
Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol
Molecular Function: protein binding; beta-catenin binding
Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding
Research Articles on CTNNBIP1/ICAT
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Product Notes
The CTNNBIP1/ICAT ctnnbip1 (Catalog #AAA4757935) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTNNBIP1/ICAT Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CTNNBIP1/ICAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:2000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CTNNBIP1/ICAT ctnnbip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTNNBIP1/ICAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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