Rabbit anti-Human CTDSP2 Polyclonal Antibody | anti-CTDSP2 antibody
CTDSP2 Antibody
Gene Names
CTDSP2; OS4; PSR2; SCP2
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CTDSP2; Polyclonal Antibody; CTDSP2 Antibody; Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma 4; conserved gene amplified in osteosarcoma; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting factor 2; NLI-interacting factor 2; Nuclear LIM interactor interacting factor 2; Nuclear LIM interactor-interacting factor 2; OS4; Protein OS 4; Protein OS-4; PSR2; SCP2; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2; anti-CTDSP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CTDSP2 Antibody detects endogenous levels of CTDSP2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CTDSP2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human CTDSP2.
Conjugation
Unconjugated
Subunit Structure
Monomer (By similarity). Interacts with REST.
Tissue Specificity
Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,664 Da
NCBI Official Full Name
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
NCBI Official Synonym Full Names
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
NCBI Official Symbol
CTDSP2
NCBI Official Synonym Symbols
OS4; PSR2; SCP2
NCBI Protein Information
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; NLI-interacting factor 2; conserved gene amplified in osteosarcoma; nuclear LIM interactor-interacting factor 2; protein OS-4; small C-terminal domain phosphatase 2; small CTD ph
UniProt Protein Name
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
UniProt Gene Name
CTDSP2
UniProt Synonym Gene Names
NIF2; OS4; SCP2; NLI-interacting factor 2; SCP2
UniProt Entry Name
CTDS2_HUMAN
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Product Notes
The CTDSP2 ctdsp2 (Catalog #AAA9630147) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTDSP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTDSP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CTDSP2 ctdsp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTDSP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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