Rabbit anti-Human, Mouse CSRP2BP Polyclonal Antibody | anti-CSRP2BP antibody

CSRP2BP, ID (ADA2A-containing Complex Subunit 2, ATAC2, CRP2-binding Partner, CRP2BP, Cysteine-rich Protein 2-binding Protein, CSRP2-binding Protein) (PE)

Cat. Num. AAA6471410

• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Immunoaffinity chromatography.
• Synonyms: CSRP2BP; Polyclonal Antibody; ID (ADA2A-containing Complex Subunit 2; ATAC2; CRP2-binding Partner; CRP2BP; Cysteine-rich Protein 2-binding Protein; CSRP2-binding Protein) (PE); anti-CSRP2BP antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CSRP2BP. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 782

• Applicable Applications for anti-CSRP2BP antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-1:500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the center region of human CSRP2BP (KLH).
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of CSRP2BP Antibody (Center) in Y79, A2058, A375, MDA-MB231 cell line lysates (35ug/lane). CSRP2BP (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CSRP2BP Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Product Categories/Family for anti-CSRP2BP antibody

Antibodies; Binding Proteins

References

1. Venkatesan, K., et.al., Nat. Methods 6(1), 83-90 (2009).

NCBI and Uniprot Product Information

• NCBI GI #: 24308203
• NCBI Accession #: NP_065397.1
• NCBI GenBank Nucleotide #: NP_065397.1
• UniProt Accession #: Q9H8E8
• Molecular Weight: 74.2822
• NCBI Official Full Name: CSRP2 binding protein isoform a
• UniProt Protein Name: Cysteine-rich protein 2-binding protein
• UniProt Gene Name: CSRP2BP
• UniProt Synonym Gene Names: CSRP2-binding protein; ATAC2; CRP2BP
• UniProt Entry Name: CSR2B_HUMAN

Uniprot Description

CSRP2BP: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: cytoplasm; nucleus

Molecular Function: histone acetyltransferase activity; LIM domain binding; protein binding

Biological Process: establishment and/or maintenance of chromatin architecture; G2/M transition of mitotic cell cycle