Rabbit anti-Human CSRP2 Polyclonal Antibody | anti-CSRP2 antibody

CSRP2, ID (CSRP2, LMO5, SMLIM, Cysteine and glycine-rich protein 2, Cysteine-rich protein 2, LIM domain only protein 5, Smooth muscle cell LIM protein) (MaxLight 550)

Cat. Num. AAA6289469

• Gene Names: CSRP2; CRP2; LMO5; SmLIM
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CSRP2; Polyclonal Antibody; ID (CSRP2; LMO5; SMLIM; Cysteine and glycine-rich protein 2; Cysteine-rich protein 2; LIM domain only protein 5; Smooth muscle cell LIM protein) (MaxLight 550); Smooth muscle cell LIM protein; anti-CSRP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

• Applicable Applications for anti-CSRP2 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: CSRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human CSRP2.
• Conjugate: MaxLight550
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-CSRP2 antibody

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3.

Product Categories/Family for anti-CSRP2 antibody

Antibodies; Amino Acids

References

Stearns, M.E., et al. Mol. Cancer Res. 1(9):631-642(2003). Wang, M., et al. Cancer Biol. Ther. 1(5):556-563(2002). Weiskirchen, R., et al. Biochem. J. 359 (PT 3), 485-496 (2001): Weiskirchen, R., et al. Biochem. Biophys. Res. Commun. 274(3):655-663(2000). Weiskirchen, R., et al. Genomics 44(1):83-93(1997).

NCBI and Uniprot Product Information

• NCBI GI #: 4503101
• NCBI GeneID: 1466
• NCBI Accession #: NP_001312.1
• NCBI GenBank Nucleotide #: NM_001321.2
• UniProt Accession #: Q16527; Q93030
• Molecular Weight: 20,954 Da
• NCBI Official Full Name: cysteine and glycine-rich protein 2
• NCBI Official Synonym Full Names: cysteine and glycine-rich protein 2
• NCBI Official Symbol: CSRP2
• NCBI Official Synonym Symbols: CRP2; LMO5; SmLIM
• NCBI Protein Information: cysteine and glycine-rich protein 2; LMO-5; cysteine-rich protein 2; LIM domain only protein 5; smooth muscle cell LIM protein; LIM domain only 5, smooth muscle
• UniProt Protein Name: Cysteine and glycine-rich protein 2
• Protein Family: Cysteine and glycine-rich protein
• UniProt Gene Name: CSRP2
• UniProt Synonym Gene Names: LMO5; SMLIM; CRP2; LMO-5; SmLIM
• UniProt Entry Name: CSRP2_HUMAN

NCBI Description

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

CSRP2: a LIM protein that is differentially regulated and preferentially expressed in aortic smooth muscle cells. Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 12q21.1

Cellular Component: focal adhesion; nucleus

Molecular Function: zinc ion binding

Biological Process: multicellular organismal development; cell differentiation