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Immunohistochemistry (IHC) (Anti-CSRP2 antibody IHC of human lung, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Goat CSRP2 Polyclonal Antibody | anti-CSRP2 antibody

Goat Polyclonal to Human CSRP2

Gene Names
CSRP2; CRP2; LMO5; SmLIM
Reactivity
Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit
Predicted Reactivity: Rat (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
CSRP2; Polyclonal Antibody; Goat Polyclonal to Human CSRP2; Anti-CSRP2 Antibody (Internal) IHC-plus; CRP2; LIM domain only protein 5; LMO-5; Smooth muscle cell LIM protein; SmLIM; LMO5; Cysteine-rich protein 2; Human CSRP2; anti-CSRP2 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit
Predicted Reactivity: Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human CSRP2.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
193
Applicable Applications for anti-CSRP2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:64000), IHC-P (3.75 ug/ml), WB (0.1 - 0.3 ug/ml)
Target Species
Human
Immunogen Description
Synthetic peptide C-ERLGIKPESVQP from an internal region of human CSRP2 (NP_001312.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Bat, Bovine, Horse, Rabbit, Pig (100%); Mouse, Rat, Panda, Opossum, Platypus (92%).
Immunogen Type
Synthetic peptide
Immunogen
CSRP2 antibody was raised against synthetic peptide C-ERLGIKPESVQP from an internal region of human CSRP2 (NP_001312.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Bat, Bovine, Horse, Rabbit, Pig (100%); Mouse, Rat, Panda, Opossum, Platypus (92%); Dog (83%).
Antigen Modification
Internal
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-CSRP2 antibody IHC of human lung, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC) (Anti-CSRP2 antibody IHC of human lung, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Western Blot (WB)

(Antibody (0.1 ug/ml) staining of mouse kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) (Antibody (0.1 ug/ml) staining of mouse kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-CSRP2 antibody
CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,954 Da
NCBI Official Full Name
cysteine and glycine-rich protein 2
NCBI Official Synonym Full Names
cysteine and glycine-rich protein 2
NCBI Official Symbol
CSRP2
NCBI Official Synonym Symbols
CRP2; LMO5; SmLIM
NCBI Protein Information
cysteine and glycine-rich protein 2; LMO-5; cysteine-rich protein 2; LIM domain only protein 5; smooth muscle cell LIM protein; LIM domain only 5, smooth muscle
UniProt Protein Name
Cysteine and glycine-rich protein 2
UniProt Gene Name
CSRP2
UniProt Synonym Gene Names
LMO5; SMLIM; CRP2; LMO-5; SmLIM
UniProt Entry Name
CSRP2_HUMAN

NCBI Description

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

CSRP2: a LIM protein that is differentially regulated and preferentially expressed in aortic smooth muscle cells. Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 12q21.1

Cellular Component: focal adhesion; nucleus

Molecular Function: zinc ion binding

Biological Process: multicellular organismal development; cell differentiation

Research Articles on CSRP2

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Product Notes

The CSRP2 csrp2 (Catalog #AAA243503) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human CSRP2 reacts with Bat, Gibbon, Bovine, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit Predicted Reactivity: Rat (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's CSRP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:64000), IHC-P (3.75 ug/ml), WB (0.1 - 0.3 ug/ml). Researchers should empirically determine the suitability of the CSRP2 csrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSRP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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