Rabbit anti-Human CSRNP1 Polyclonal Antibody | anti-CSRNP1 antibody

CSRNP1 Polyclonal Antibody

Cat. Num. AAA2536084

• Gene Names: CSRNP1; AXUD1; URAX1; TAIP-3; CSRNP-1; FAM130B
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purification
• Synonyms: CSRNP1; Polyclonal Antibody; CSRNP1 Polyclonal Antibody; AXUD1; URAX1; TAIP-3; CSRNP-1; FAM130B; anti-CSRNP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification

• Applicable Applications for anti-CSRNP1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-100
• Immunogen: Recombinant protein of human CSRNP1
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49279 / sc-49281
• Preparation and Storage: Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cell using CSRNP1 antibody.)

Related Product Information for anti-CSRNP1 antibody

This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function.

NCBI and Uniprot Product Information

• NCBI GI #: 1001624607
• NCBI GeneID: 64651
• NCBI Accession #: NP_001307489.1
• NCBI GenBank Nucleotide #: NM_001320560.1
• Molecular Weight: Calculated MW: 64kDa
• NCBI Official Full Name: cysteine/serine-rich nuclear protein 1 isoform b
• NCBI Official Synonym Full Names: cysteine and serine rich nuclear protein 1
• NCBI Official Symbol: CSRNP1
• NCBI Official Synonym Symbols: AXUD1; URAX1; TAIP-3; CSRNP-1; FAM130B
• NCBI Protein Information: cysteine/serine-rich nuclear protein 1
• UniProt Protein Name: Cysteine/serine-rich nuclear protein 1
• Protein Family: Cysteine/serine-rich nuclear protein
• UniProt Gene Name: CSRNP1
• UniProt Synonym Gene Names: AXUD1; TAIP3; CSRNP-1; TAIP-3
• UniProt Entry Name: CSRN1_HUMAN

NCBI Description

This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Description

AXUD1: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. Belongs to the AXUD1 family.

Chromosomal Location of Human Ortholog: 3p22

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: apoptosis; palate development; platelet-derived growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; skeletal morphogenesis; transcription from RNA polymerase II promoter