Western Blot (WB)
(Mouse Csnk2a2 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Csnk2a2 antibody detected the Csnk2a2 protein (arrow).)
Rabbit Csnk2a2 Polyclonal Antibody | anti-Csnk2a2 antibody
Mouse Csnk2a2 Antibody (N-term)
Western Blot (WB)
(Mouse Csnk2a2 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Csnk2a2 antibody detected the Csnk2a2 protein (arrow).)
Western Blot (WB)
(Mouse Csnk2a2 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Csnk2a2 antibody detected the Csnk2a2 protein (arrow).)
Western Blot (WB)
(Mouse Csnk2a2 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Csnk2a2 antibody detected the Csnk2a2 protein (arrow).)
Western Blot (WB)
(Mouse Csnk2a2 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Csnk2a2 antibody detected the Csnk2a2 protein (arrow).)
Cobb, L.J., et al. Mol. Endocrinol. 23(10):1624-1633(2009)
Mueller, T., et al. Hum. Mol. Genet. 18(17):3334-3343(2009)
Maier, B., et al. Genes Dev. 23(6):708-718(2009)
Kang, H., et al. PLoS ONE 4 (8), E6611 (2009) :
NCBI and Uniprot Product Information
Uniprot Description
CK2A2: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
Protein type: Protein kinase, Other; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; CK2 family
Cellular Component: protein kinase CK2 complex; PcG protein complex; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; protein N-terminus binding; kinase activity; ATP binding; protein kinase activity
Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; regulation of cell cycle; cell cycle; protein amino acid phosphorylation; phosphorylation
Research Articles on Csnk2a2
Similar Products
Product Notes
The Csnk2a2 csnk2a2 (Catalog #AAA9208498) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 4-32. The Mouse Csnk2a2 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Bovine, Chicken) and may cross-react with other species as described in the data sheet. AAA Biotech's Csnk2a2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Csnk2a2 csnk2a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Csnk2a2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
