Western Blot (WB)
(CSH1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CSH1 antibody detected the CSH1 protein (arrow).)
Rabbit anti-Human CSH1 Polyclonal Antibody | anti-CSH1 antibody
CSH1, CT (CSH1, Chorionic somatomammotropin hormone, Lactogen, Placental lactogen) (APC)
Gene Names
CSH1; PL; CSA; CS-1; CSMT; hCS-A
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CSH1; Polyclonal Antibody; CT (CSH1; Chorionic somatomammotropin hormone; Lactogen; Placental lactogen) (APC); Placental lactogen; anti-CSH1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CSH1 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
CSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-208 amino acids from the C-terminal region of human CSH1.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(CSH1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CSH1 antibody detected the CSH1 protein (arrow).)
Western Blot (WB)
(CSH1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CSH1 antibody detected the CSH1 protein (arrow).)
Western Blot (WB)
(Western blot analysis of CSH1 (arrow) using rabbit polyclonal CSH1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSH1 gene.)
Western Blot (WB)
(Western blot analysis of CSH1 (arrow) using rabbit polyclonal CSH1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSH1 gene.)
Immunohistochemistry (IHC)
(CSH1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CSH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CSH1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CSH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-CSH1 antibody
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq].
Product Categories/Family for anti-CSH1 antibody
References
Voorhees, J.L., et al. J. Biol. Chem. 285(26):20022-20030(2010). Mannik, J., et al. J. Clin. Endocrinol. Metab. 95(5):2433-2442(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Varvarigou, A.A., et al. J Perinat Med 37(4):364-369(2009). Chen, Y., et al. Cancer Res. 68(23):9729-9734(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,020 Da
NCBI Official Full Name
chorionic somatomammotropin hormone
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1 (placental lactogen)
NCBI Official Symbol
CSH1
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; hCS-A
NCBI Protein Information
chorionic somatomammotropin hormone; choriomammotropin; placental lactogen; chorionic somatomammotropin A
UniProt Protein Name
Chorionic somatomammotropin hormone
Protein Family
UniProt Gene Name
CSH1
UniProt Synonym Gene Names
Choriomammotropin; PL
UniProt Entry Name
CSH_HUMAN
Uniprot Description
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular region
Molecular Function: hormone activity; metal ion binding
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Product Notes
The CSH1 csh1 (Catalog #AAA6289265) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CSH1, CT (CSH1, Chorionic somatomammotropin hormone, Lactogen, Placental lactogen) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CSH1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-100 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CSH1 csh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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