Western Blot (WB)
(Western blot analysis of CSGALNACT1 using HepG2 whole cell lysates)
Rabbit anti-Human CSGALNACT1 Polyclonal Antibody | anti-CSGALNACT1 antibody
CSGALNACT1 Antibody
Gene Names
CSGALNACT1; ChGn; ChGn-1; CSGalNAcT-1; beta4GalNAcT
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CSGALNACT1; Polyclonal Antibody; CSGALNACT1 Antibody; 4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT 1; beta4GalNAcT; Beta4GalNAcT-1; Beta4GalNAcT1; CGAT1_HUMAN; ChGn; Chondroitin beta-1; Chondroitin beta1 4 N acetylgalactosaminyltransferase; Chondroitin beta1 4 N acetylgalactosaminyltransferase 1; Chondroitin sulfate N acetylgalactosaminyltransferase 1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CSGalNAcT 1; CsGalNAcT-1; Csgalnact1; FLJ11264; FLJ13760; anti-CSGALNACT1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CSGALNACT1 antibody detects endogenous levels of total CSGALNACT1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
532
Applicable Applications for anti-CSGALNACT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000
Immunogen
A synthesized peptide derived from human CSGALNACT1
Subcellular Location
Golgi Apparatus > Golgi Stack Membrane.
Tissue Specificity
Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Similarity
Pig (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (91%), Xenopus (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of CSGALNACT1 using HepG2 whole cell lysates)
Western Blot (WB)
(Western blot analysis of CSGALNACT1 using HepG2 whole cell lysates)
Related Product Information for anti-CSGALNACT1 antibody
Function: Transfers 1, 4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification (PubMed:11788602, PubMed:12163485, PubMed:12446672, PubMed:17145758). Moreover, is involved in the metabolism of aggrecan (By similarity).
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 61 kDa
Predicted: 62 kDa
Predicted: 62 kDa
NCBI Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Official Synonym Full Names
chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Official Symbol
CSGALNACT1
NCBI Official Synonym Symbols
ChGn; ChGn-1; CSGalNAcT-1; beta4GalNAcT
NCBI Protein Information
chondroitin sulfate N-acetylgalactosaminyltransferase 1
UniProt Protein Name
Chondroitin sulfate N-acetylgalactosaminyltransferase 1
Protein Family
UniProt Gene Name
CSGALNACT1
UniProt Synonym Gene Names
CsGalNAcT-1Curated; Beta4GalNAcT-1
NCBI Description
This gene encodes an enzyme that transfers N-acetylglucosamine (GalNAc) to the core tetrasaccharide linker and to elongating chondroitin sulfate chains in proteoglycans. Knockout of the orthologous mouse gene indicates that the protein is necessary for normal cartilage development and aggrecan metabolism. Mutations in this gene are associated with multiple sclerosis progression, and with mild skeletal dysplasia and joint laxity. [provided by RefSeq, Aug 2017]
Uniprot Description
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification (PubMed:11788602, PubMed:12163485, PubMed:12446672, PubMed:17145758). Moreover, is involved in the metabolism of aggrecan ().
Research Articles on CSGALNACT1
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Product Notes
The CSGALNACT1 csgalnact1 (Catalog #AAA9602281) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CSGALNACT1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CSGALNACT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the CSGALNACT1 csgalnact1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSGALNACT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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