Western Blot (WB)
(Western blot analysis of CPZ Antibody (N-term) in K562 cell line lysates (35ug/lane). CPZ (arrow) was detected using the purified Pab.)
Rabbit anti-Human CPZ Polyclonal Antibody | anti-CPZ antibody
CPZ, NT (Carboxypeptidase Z)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Western Blot (WB)
(Western blot analysis of CPZ Antibody (N-term) in K562 cell line lysates (35ug/lane). CPZ (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of CPZ Antibody (N-term) in K562 cell line lysates (35ug/lane). CPZ (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Uniprot Description
CPZ: Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.17.-; Protease; Secreted; Extracellular matrix; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4p16.1
Cellular Component: proteinaceous extracellular matrix
Molecular Function: zinc ion binding; metallocarboxypeptidase activity
Biological Process: Wnt receptor signaling pathway; proteolysis
Research Articles on CPZ
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Product Notes
The CPZ cpz (Catalog #AAA629411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPZ, NT (Carboxypeptidase Z) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CPZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the CPZ cpz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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