Western Blot (WB)
(Western blot analysis of Cox-3 with mouse small intestine tissue lysate.)
Rabbit COX3 Polyclonal Antibody | anti-COX3 antibody
COX3 antibody
Applications
Western Blot
Purity
COX3 antibody was purified by affinity chromatography
Synonyms
COX3; Polyclonal Antibody; COX3 antibody; Polyclonal COX3; anti-COX3; PHS1; PGHS1; PCOX1; COX-3; PGHS-1; PTGS1; PTGHS; COX 3; anti-COX3 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
COX3 antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
269
Applicable Applications for anti-COX3 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID such as aspirin. Prostaglandins formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis. In rodents and humans, COX-3 encodes proteins with completely different amino acid sequences than COX-1 or COX-2 and without COX activity. It has been suggested COX-3 as the key to unlocking the mystery of the mechanism of action of acetaminophen.
Cross-Reactivity
Mouse
Immunogen
COX3 antibody was raised in Rabbit using synthetic peptide mapping to the N-terminus of mouse Cox-3 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Cox-3 with mouse small intestine tissue lysate.)
Western Blot (WB)
(Western blot analysis of Cox-3 with mouse small intestine tissue lysate.)
Related Product Information for anti-COX3 antibody
Rabbit polyclonal COX3 antibody
Product Categories/Family for anti-COX3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,733 Da
NCBI Official Full Name
Cox3 (mitochondrion)
NCBI Official Symbol
cox3
NCBI Protein Information
Cox3
UniProt Protein Name
Cytochrome c oxidase subunit 3
Protein Family
UniProt Gene Name
cox3
UniProt Entry Name
V5W791_9HELO
Uniprot Description
Subunits I, II and III form the functional core of the enzyme complex.
Similar Products
Product Notes
The COX3 cox3 (Catalog #AAA5302381) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's COX3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the COX3 cox3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
