Rabbit anti-Human COX20 Polyclonal Antibody | anti-COX20 antibody

COX20 Rabbit Polyclonal

Cat. Num. AAA768130

• Gene Names: COX20; FAM36A
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: COX20; Polyclonal Antibody; COX20 Rabbit Polyclonal; anti-COX20 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 61

• Applicable Applications for anti-COX20 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Family with sequence similarity 36, member A
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using MBS768130 (FAM36A Antibody) at dilution of 1:50)

Western Blot (WB)

(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS768130 (FAM36A Antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

• NCBI GI #: 918410281
• NCBI GeneID: 116228
• NCBI Accession #: NP_001299803.1
• NCBI GenBank Nucleotide #: NM_001312874.1
• Molecular Weight: 14,669 Da
• NCBI Official Full Name: cytochrome c oxidase protein 20 homolog isoform 4
• NCBI Official Synonym Full Names: COX20 cytochrome c oxidase assembly factor
• NCBI Official Symbol: COX20
• NCBI Official Synonym Symbols: FAM36A
• NCBI Protein Information: cytochrome c oxidase protein 20 homolog
• UniProt Protein Name: Cytochrome c oxidase protein 20 homolog
• Protein Family: Cytochrome c oxidase protein
• UniProt Gene Name: COX20
• UniProt Synonym Gene Names: FAM36A
• UniProt Entry Name: COX20_HUMAN

NCBI Description

This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Uniprot Description

FAM36A: Belongs to the COX20 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: integral to membrane; mitochondrial membrane; mitochondrion

Biological Process: aerobic respiration; mitochondrial respiratory chain complex IV assembly

Disease: Mitochondrial Complex Iv Deficiency