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Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using COTL1 antibody.)
Rabbit COTL1 Polyclonal Antibody | anti-COTL1 antibody
COTL1 Polyclonal Antibody
Gene Names
COTL1; CLP
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purification
Synonyms
COTL1; Polyclonal Antibody; COTL1 Polyclonal Antibody; CLP; coactosin-like protein; anti-COTL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-COTL1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:100
IHC: 1:50-1:100
Immunogen
Recombinant fusion protein of human COTL1 (NP_066972.1).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using COTL1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse brain using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse brain using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver damage using COTL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver damage using COTL1 antibody.)
Related Product Information for anti-COTL1 antibody
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Product Categories/Family for anti-COTL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,945 Da
NCBI Official Full Name
coactosin-like protein
NCBI Official Synonym Full Names
coactosin like F-actin binding protein 1
NCBI Official Symbol
COTL1
NCBI Official Synonym Symbols
CLP
NCBI Protein Information
coactosin-like protein
UniProt Protein Name
Coactosin-like protein
Protein Family
UniProt Gene Name
COTL1
UniProt Synonym Gene Names
CLP
UniProt Entry Name
COTL1_HUMAN
Uniprot Description
COTL1: Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Belongs to the actin-binding proteins ADF family. Coactosin subfamily.
Protein type: Actin-binding
Chromosomal Location of Human Ortholog: 16q24.1
Cellular Component: nuclear membrane; cytoskeleton; cytoplasm
Molecular Function: protein binding; enzyme binding; actin binding
Biological Process: defense response to fungus
Similar Products
Product Notes
The COTL1 cotl1 (Catalog #AAA9433712) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COTL1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's COTL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the COTL1 cotl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COTL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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