Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS1497628 at dilution 1:100)
Rabbit anti-Human Conserved oligomeric Golgi complex subunit 7 Polyclonal Antibody | anti-COG7 antibody
Rabbit anti-human Conserved oligomeric Golgi complex subunit 7 polyclonal Antibody(COG7)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS1497628 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS1497628 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS1497628 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS1497628 at dilution 1:100)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene resides in the golgi, and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localization. Mutations in this gene are associated with the congenital disorder of glycosylation type IIe.[provided by RefSeq, May 2010]
Uniprot Description
COG7: Required for normal Golgi function. Defects in COG7 are the cause of congenital disorder of glycosylation type 2E (CDG2E). CDGs are a family of severe inherited diseases caused by a defect in protein N- glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Belongs to the COG7 family.
Chromosomal Location of Human Ortholog: 16p12.2
Cellular Component: Golgi apparatus; Golgi membrane; Golgi transport complex; intracellular membrane-bound organelle; nucleolus
Molecular Function: protein binding
Biological Process: cellular protein metabolic process; ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; intracellular protein transport; post-translational protein modification; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine; protein localization in Golgi apparatus; protein localization in organelle; protein stabilization; retrograde vesicle-mediated transport, Golgi to ER
Disease: Congenital Disorder Of Glycosylation, Type Iie
Research Articles on COG7
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Product Notes
The COG7 cog7 (Catalog #AAA1497628) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Conserved oligomeric Golgi complex subunit 7 polyclonal Antibody(COG7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Conserved oligomeric Golgi complex subunit 7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the COG7 cog7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Conserved oligomeric Golgi complex subunit 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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