Immunohistochemistry (IHC)
(Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human COL8A2/Collagen VIII Polyclonal Antibody | anti-COL8A2 antibody
Anti-COL8A2/Collagen VIII Antibody (aa571-599)
IHC-P: 1:10-1:50
WB: 1:1000
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF)
(Confocal immunofluorescence of COL8A2 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
Immunofluorescence (IF)
(Confocal immunofluorescence of COL8A2 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
Western Blot (WB)
(COL8A2 Antibody western blot of CEM cell line lysates (35 ug/lane). The COL8A2 antibody detected the COL8A2 protein (arrow).)
Western Blot (WB)
(COL8A2 Antibody western blot of CEM cell line lysates (35 ug/lane). The COL8A2 antibody detected the COL8A2 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Uniprot Description
Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis ().
Research Articles on COL8A2
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Product Notes
The COL8A2 col8a2 (Catalog #AAA2401429) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-COL8A2/Collagen VIII Antibody (aa571-599) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COL8A2/Collagen VIII can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IF: 1:10-1:50 IHC-P: 1:10-1:50 WB: 1:1000. Researchers should empirically determine the suitability of the COL8A2 col8a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COL8A2/Collagen VIII, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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