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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using CNPY3 antibody.)

Rabbit CNPY3 Polyclonal Antibody | anti-CNPY3 antibody

CNPY3 Polyclonal Antibody

Gene Names
CNPY3; CAG4A; ERDA5; TNRC5; EIEE60; PRAT4A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CNPY3; Polyclonal Antibody; CNPY3 Polyclonal Antibody; Protein canopy homolog 3; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein; CTG4A; ERDA5; PRAT4A; TNRC5; HSPC084; UNQ1934/PRO4409; anti-CNPY3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CNPY3 polyclonal antibody detects endogenous levels of CNPY3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
278
Applicable Applications for anti-CNPY3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Recombinant full length Human CNPY3.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using CNPY3 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using CNPY3 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse kidney using CNPY3 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse kidney using CNPY3 antibody.)
Related Product Information for anti-CNPY3 antibody
PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 38kDa
NCBI Official Full Name
Protein canopy homolog 3
NCBI Official Synonym Full Names
canopy FGF signaling regulator 3
NCBI Official Symbol
CNPY3
NCBI Official Synonym Symbols
CAG4A; ERDA5; TNRC5; EIEE60; PRAT4A
NCBI Protein Information
protein canopy homolog 3
UniProt Protein Name
Protein canopy homolog 3
Protein Family
UniProt Gene Name
CNPY3
UniProt Synonym Gene Names
CTG4A; ERDA5; PRAT4A; TNRC5
UniProt Entry Name
CNPY3_HUMAN

NCBI Description

This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]

Uniprot Description

TNRC5: Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: endoplasmic reticulum lumen

Molecular Function: receptor binding

Biological Process: toll-like receptor signaling pathway; innate immune response

Research Articles on CNPY3

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Product Notes

The CNPY3 cnpy3 (Catalog #AAA3011984) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNPY3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNPY3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CNPY3 cnpy3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNPY3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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