Western Blot (WB)
(Western blot analysis of CNP-53 using HepG2 whole cell lysates)
Rabbit CNP-53 Polyclonal Antibody | anti-CNP-53 antibody
CNP-53 Antibody
Gene Names
NPPC; CNP; CNP2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CNP-53; Polyclonal Antibody; CNP-53 Antibody; ANFC_HUMAN; C type natriuretic peptide precursor; CNP; CNP2; Natriuretic peptide C; Natriuretic peptide precursor C; NPPC; anti-CNP-53 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CNP-53 antibody detects endogenous levels of total CNP-53
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
126
Applicable Applications for anti-CNP-53 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human CNP-53
Subcellular Location
Secreted.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of CNP-53 using HepG2 whole cell lysates)
Western Blot (WB)
(Western blot analysis of CNP-53 using HepG2 whole cell lysates)
Related Product Information for anti-CNP-53 antibody
Function: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity).
Similarity: Belongs to the natriuretic peptide family.
Similarity: Belongs to the natriuretic peptide family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 13 kDa
Predicted: 14 kDa
Predicted: 14 kDa
NCBI Official Full Name
C-type natriuretic peptide preproprotein
NCBI Official Synonym Full Names
natriuretic peptide C
NCBI Official Symbol
NPPC
NCBI Official Synonym Symbols
CNP; CNP2
NCBI Protein Information
C-type natriuretic peptide
UniProt Protein Name
C-type natriuretic peptide
UniProt Gene Name
NPPC
UniProt Synonym Gene Names
CNP2
NCBI Description
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]
Uniprot Description
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 ().
Research Articles on CNP-53
Similar Products
Product Notes
The CNP-53 nppc (Catalog #AAA9608840) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNP-53 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNP-53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the CNP-53 nppc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNP-53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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