Western Blot (WB)
(Host: RabbitTarget Name: RQCD1Sample Tissue: Human Neurofibroma Tumor lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human CNOT9 Polyclonal Antibody | anti-CNOT9 antibody
CNOT9 Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: RQCD1Sample Tissue: Human Neurofibroma Tumor lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: RQCD1Sample Tissue: Human Neurofibroma Tumor lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]
Uniprot Description
RQCD1: Transcription factor that down-regulates MYB- and JUN- dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. Belongs to the RCD1 family.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: membrane; nucleus; cytosol; CCR4-NOT complex
Molecular Function: protein domain specific binding; protein binding; protein homodimerization activity
Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; gene expression; RNA-mediated gene silencing; sex differentiation; mRNA catabolic process, deadenylation-dependent decay; negative regulation of estrogen receptor signaling pathway
Research Articles on CNOT9
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Product Notes
The CNOT9 rqcd1 (Catalog #AAA3222084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNOT9 Antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNOT9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CNOT9 rqcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: YQWINELSSP ETRENALLEL SKKRESVPDL APMLWHSFGT IAALLQEIVN. It is sometimes possible for the material contained within the vial of "CNOT9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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