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Western Blot (WB) (RQCD1 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).)

Rabbit anti-Human, Mouse RQCD1 Polyclonal Antibody | anti-RQCD1 antibody

RQCD1, ID (RQCD1, CNOT9, RCD1, Cell differentiation protein RCD1 homolog, CCR4-NOT transcription complex subunit 9) (AP)

Gene Names
CNOT9; RCD1; CAF40; CT129; RCD-1; RQCD1
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RQCD1; Polyclonal Antibody; ID (RQCD1; CNOT9; RCD1; Cell differentiation protein RCD1 homolog; CCR4-NOT transcription complex subunit 9) (AP); CCR4-NOT transcription complex subunit 9; anti-RQCD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-RQCD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
RQCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-134 amino acids from the Central region of human RQCD1.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RQCD1 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).)

Western Blot (WB) (RQCD1 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).)

Western Blot (WB)

(RQCD1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).)

Western Blot (WB) (RQCD1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the RQCD1 antibody detected the RQCD1 protein (arrow).)
Related Product Information for anti-RQCD1 antibody
Transcription factor that down-regulates MYB-and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A.
Product Categories/Family for anti-RQCD1 antibody
References
Ajiro, M., et al. Int. J. Oncol. 35(4):673-681(2009). Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008). Garapaty, S., et al. J. Biol. Chem. 283(11):6806-6816(2008). Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007). Hiroi, N., et al. EMBO J. 21(19):5235-5244(2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32 kDa
NCBI Official Full Name
CCR4-NOT transcription complex subunit 9 isoform 2
NCBI Official Synonym Full Names
CCR4-NOT transcription complex subunit 9
NCBI Official Symbol
CNOT9
NCBI Official Synonym Symbols
RCD1; CAF40; CT129; RCD-1; RQCD1
NCBI Protein Information
CCR4-NOT transcription complex subunit 9
UniProt Protein Name
Cell differentiation protein RCD1 homolog
UniProt Gene Name
RQCD1
UniProt Synonym Gene Names
CNOT9; RCD1; Rcd-1
UniProt Entry Name
RCD1_HUMAN

NCBI Description

This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]

Uniprot Description

RQCD1: Transcription factor that down-regulates MYB- and JUN- dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. Belongs to the RCD1 family.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: membrane; nucleus; cytosol; CCR4-NOT complex

Molecular Function: protein domain specific binding; protein binding; protein homodimerization activity

Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; gene expression; RNA-mediated gene silencing; sex differentiation; mRNA catabolic process, deadenylation-dependent decay; negative regulation of estrogen receptor signaling pathway

Research Articles on RQCD1

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Product Notes

The RQCD1 rqcd1 (Catalog #AAA6344018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RQCD1, ID (RQCD1, CNOT9, RCD1, Cell differentiation protein RCD1 homolog, CCR4-NOT transcription complex subunit 9) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RQCD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RQCD1 rqcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RQCD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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