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Western Blot (WB) (WB Suggested Anti-CNKSR2 AntibodyTitration: 1.0 ug/mlPositive Control: 721_B Whole Cell)

Rabbit CNKSR2 Polyclonal Antibody | anti-CNKSR2 antibody

CNKSR2 Antibody - C-terminal region

Gene Names
CNKSR2; CNK2; KSR2; MAGUIN; MRXSHG
Reactivity
Cow, Dog, Horse, Human, Mouse, Rabbit, Rat
Applications
Western Blot
Purity
Affinity Purified
Synonyms
CNKSR2; Polyclonal Antibody; CNKSR2 Antibody - C-terminal region; anti-CNKSR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Horse, Human, Mouse, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: EEEEEEGEAAGENIGEKSESREEKLGDSLQDLYRALEQASLSPLGEHRIS
Sequence Length
1034
Applicable Applications for anti-CNKSR2 antibody
Western Blot (WB)
Homology
Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CNKSR2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-CNKSR2 AntibodyTitration: 1.0 ug/mlPositive Control: 721_B Whole Cell)

Western Blot (WB) (WB Suggested Anti-CNKSR2 AntibodyTitration: 1.0 ug/mlPositive Control: 721_B Whole Cell)
Related Product Information for anti-CNKSR2 antibody
This is a rabbit polyclonal antibody against CNKSR2. It was validated on Western Blot

Target Description: This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-CNKSR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
114kDa
NCBI Official Full Name
connector enhancer of kinase suppressor of ras 2 isoform 1
NCBI Official Synonym Full Names
connector enhancer of kinase suppressor of Ras 2
NCBI Official Symbol
CNKSR2
NCBI Official Synonym Symbols
CNK2; KSR2; MAGUIN; MRXSHG
NCBI Protein Information
connector enhancer of kinase suppressor of ras 2
UniProt Protein Name
Connector enhancer of kinase suppressor of ras 2
UniProt Gene Name
CNKSR2
UniProt Synonym Gene Names
CNK2; KIAA0902; KSR2; Connector enhancer of KSR 2; CNK2
UniProt Entry Name
CNKR2_HUMAN

NCBI Description

This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Uniprot Description

CNKSR2: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: Golgi apparatus; postsynaptic membrane; neuron projection; cell soma; plasma membrane

Molecular Function: identical protein binding

Biological Process: regulation of signal transduction

Research Articles on CNKSR2

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Product Notes

The CNKSR2 cnksr2 (Catalog #AAA3216892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNKSR2 Antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNKSR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CNKSR2 cnksr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: EEEEEEGEAA GENIGEKSES REEKLGDSLQ DLYRALEQAS LSPLGEHRIS. It is sometimes possible for the material contained within the vial of "CNKSR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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