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Western Blot (WB) (Western blot analysis of CNDP1 Antibody (C-term) in CEM cell line lysates (35ug/lane). CNDP1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human CNDP1 Polyclonal Antibody | anti-CNDP1 antibody

CNDP1, CT (CNDP1, CN1, CPGL2, Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase) (Azide free) (HRP)

Gene Names
CNDP1; CN1; CPGL2; HsT2308
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CNDP1; Polyclonal Antibody; CT (CNDP1; CN1; CPGL2; Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase) (Azide free) (HRP); Serum carnosinase; anti-CNDP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-CNDP1 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:50-100
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
CNDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422~451 amino acids from the C-terminal region of human CNDP1.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of CNDP1 Antibody (C-term) in CEM cell line lysates (35ug/lane). CNDP1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of CNDP1 Antibody (C-term) in CEM cell line lysates (35ug/lane). CNDP1 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human brain tissue reacted with CNDP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human brain tissue reacted with CNDP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(CNDP1 Antibody (C-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (CNDP1 Antibody (C-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-CNDP1 antibody
CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism in the coding region.
Product Categories/Family for anti-CNDP1 antibody
References
Craig, D.W., et.al., Diabet. Med. 26 (11), 1090-1098 (2009). Mooyaart, A.L., et.al., Diabetes Res. Clin. Pract. 85 (3), 272-278 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
56,706 Da
NCBI Official Full Name
carnosine dipeptidase 1 (metallopeptidase M20 family), isoform CRA_a
NCBI Official Synonym Full Names
carnosine dipeptidase 1 (metallopeptidase M20 family)
NCBI Official Symbol
CNDP1
NCBI Official Synonym Symbols
CN1; CPGL2; HsT2308
NCBI Protein Information
beta-Ala-His dipeptidase; carnosinase 1; serum carnosinase; CNDP dipeptidase 1; glutamate carboxypeptidase-like protein 2
UniProt Protein Name
Beta-Ala-His dipeptidase
Protein Family
UniProt Gene Name
CNDP1
UniProt Synonym Gene Names
CN1; CPGL2
UniProt Entry Name
CNDP1_HUMAN

NCBI Description

This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Uniprot Description

CNDP1: a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - histidine; Protease; Secreted, signal peptide; Secreted; Other Amino Acids Metabolism - beta-alanine; EC 3.4.13.20

Chromosomal Location of Human Ortholog: 18q22.3

Cellular Component: extracellular region

Molecular Function: dipeptidase activity; metallopeptidase activity; carboxypeptidase activity; metal ion binding

Biological Process: proteolysis

Research Articles on CNDP1

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Product Notes

The CNDP1 cndp1 (Catalog #AAA6287101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNDP1, CT (CNDP1, CN1, CPGL2, Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase) (Azide free) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNDP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-100 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CNDP1 cndp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNDP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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