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Western Blot (WB) (Western blot analysis of NIH/3T3 LO2 and Jurkat cell lysates using CLTB Polyclonal Antibody at dilution of 1:800)

Rabbit anti-Human, Mouse CLTB Polyclonal Antibody | anti-CLTB antibody

CLTB Polyclonal Antibody

Gene Names
CLTB; LCB
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
CLTB; Polyclonal Antibody; CLTB Polyclonal Antibody; Clathrin Light Chain B; Clathrin; Light Polypeptide (Lcb); LCB; Light Chain (Lcb); Light Chain B; anti-CLTB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.08mg/mL (varies by lot)
Sequence Length
211
Applicable Applications for anti-CLTB antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human CLTB
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of NIH/3T3 LO2 and Jurkat cell lysates using CLTB Polyclonal Antibody at dilution of 1:800)

Western Blot (WB) (Western blot analysis of NIH/3T3 LO2 and Jurkat cell lysates using CLTB Polyclonal Antibody at dilution of 1:800)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CLTB Polyclonal Antibody at dilution of 1:60(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CLTB Polyclonal Antibody at dilution of 1:60(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using CLTB Polyclonal Antibody at dilution of 1:60(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using CLTB Polyclonal Antibody at dilution of 1:60(×200))
Related Product Information for anti-CLTB antibody
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (180 kDa) and three light chains of two types,LCA (CLTA) and LCB (CLTB) (30-40 kDa). The light chain subunits are thought to regulate the formation or disassembly of clathrin coats.
Product Categories/Family for anti-CLTB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25 kDa
NCBI Official Full Name
clathrin light chain B isoform a
NCBI Official Synonym Full Names
clathrin light chain B
NCBI Official Symbol
CLTB
NCBI Official Synonym Symbols
LCB
NCBI Protein Information
clathrin light chain B
UniProt Protein Name
Clathrin light chain B
Protein Family
UniProt Gene Name
CLTB
UniProt Synonym Gene Names
Lcb
UniProt Entry Name
CLCB_HUMAN

NCBI Description

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

CLTB: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: clathrin coat of trans-Golgi network vesicle; clathrin coat; intracellular membrane-bound organelle; cytoplasm; plasma membrane; trans-Golgi network; clathrin coat of coated pit

Molecular Function: protein binding; structural molecule activity; peptide binding

Biological Process: vesicle-mediated transport; intracellular protein transport

Research Articles on CLTB

Similar Products

Product Notes

The CLTB cltb (Catalog #AAA2562987) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLTB Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CLTB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the CLTB cltb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLTB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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