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Western Blot (WB) (Western Blot analysis of Jurkat cells using CLTC Monoclonal Antibody at dilution of 1:40000.)

Mouse CLTC Monoclonal Antibody | anti-CLTC antibody

CLTC Monoclonal Antibody

Gene Names
CLTC; Hc; CHC; CHC17; CLH-17; CLTCL2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Protein A Purification
Synonyms
CLTC; Monoclonal Antibody; CLTC Monoclonal Antibody; CHC; CHC17; Clathrin heavy chain 1; clathrin; heavy chain (Hc); CLH 17; CLH17; CLTCL2; Hc; KIAA0034; anti-CLTC antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1B3D7
Purity/Purification
Protein A Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
6529
Applicable Applications for anti-CLTC antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:20000-1:80000
Immunogen
Fusion Protein of CLTC
Buffer
PBS with 0.1% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Jurkat cells using CLTC Monoclonal Antibody at dilution of 1:40000.)

Western Blot (WB) (Western Blot analysis of Jurkat cells using CLTC Monoclonal Antibody at dilution of 1:40000.)
Related Product Information for anti-CLTC antibody
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (CLTC) (160-190 kDa) and three light chains of two types, LCA (CLTA) and LCB (CLTB) (30-40 kDa). The heavy chain provides the structural backbone of the clathrin lattice.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Calculated Molecular Weight: 192kDa
Observed Molecular Weight: 170kDa
NCBI Official Full Name
Homo sapiens clathrin, heavy chain (Hc), mRNA
NCBI Official Synonym Full Names
clathrin heavy chain
NCBI Official Symbol
CLTC
NCBI Official Synonym Symbols
Hc; CHC; CHC17; CLH-17; CLTCL2
NCBI Protein Information
clathrin heavy chain 1
UniProt Protein Name
Clathrin heavy chain 1
Protein Family
UniProt Gene Name
CLTC
UniProt Synonym Gene Names
CLH17; CLTCL2; KIAA0034; CLH-17

NCBI Description

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]

Uniprot Description

CLTC: a major protein component of the cytoplasmic face of coated vesicles and coated pits. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

Protein type: Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 17q23.1

Cellular Component: clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin-coated endocytic vesicle; clathrin-coated vesicle; cytosol; endosome; extracellular exosome; extracellular matrix; focal adhesion; lysosome; melanosome; membrane; mitotic spindle microtubule; plasma membrane; protein complex; spindle; trans-Golgi network membrane

Molecular Function: clathrin light chain binding; double-stranded RNA binding; low-density lipoprotein receptor binding; protein binding; protein kinase binding; RNA binding; structural molecule activity; ubiquitin-specific protease binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; autophagy; cell division; clathrin coat assembly; clathrin-dependent endocytosis; intracellular protein transport; low-density lipoprotein particle clearance; low-density lipoprotein particle receptor catabolic process; microtubule-based movement; mitotic cell cycle; negative regulation of hyaluronan biosynthetic process; osteoblast differentiation; receptor internalization; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; transcytosis; transferrin transport; Wnt receptor signaling pathway, planar cell polarity pathway

Research Articles on CLTC

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Product Notes

The CLTC cltc (Catalog #AAA2549062) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CLTC Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLTC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:20000-1:80000. Researchers should empirically determine the suitability of the CLTC cltc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLTC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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