Goat CLPP Polyclonal Antibody | anti-CLPP antibody
Goat anti-CLPP Antibody
Immunohistochemistry: In paraffin embedded Human Liver shows cytoplasmic staining consistent with mitochondrai in hepatocytes. Recommended concentration, 2-4ug/ml.
Western Blot: Approx 26kDa band observed in Human Heart (calculated MW of 30.2kDa according to NP_006003.1). Recommended for use at 1-3ug/ml.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
Uniprot Description
CLPP: Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Belongs to the peptidase S14 family.
Protein type: Protease; Mitochondrial; EC 3.4.21.92
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: identical protein binding; peptidase activity; protein binding; serine-type endopeptidase activity
Biological Process: protein homooligomerization; proteolysis involved in cellular protein catabolic process
Disease: Perrault Syndrome 3
Research Articles on CLPP
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Product Notes
The CLPP clpp (Catalog #AAA420213) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-CLPP Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLPP can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 1000. Immunohistochemistry: In paraffin embedded Human Liver shows cytoplasmic staining consistent with mitochondrai in hepatocytes. Recommended concentration, 2-4ug/ml. Western Blot: Approx 26kDa band observed in Human Heart (calculated MW of 30.2kDa according to NP_006003.1). Recommended for use at 1-3ug/ml. Researchers should empirically determine the suitability of the CLPP clpp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EAAPAAEPVP AST. It is sometimes possible for the material contained within the vial of "CLPP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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