anti-Human Clock Polyclonal Antibody | anti-Clock antibody
Anti - Clock
Gene Names
CLOCK; KAT13D; bHLHe8; KIAA0334
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by affinity chromatography.
Synonyms
Clock; Polyclonal Antibody; Anti - Clock; anti-Clock antibody
Host
Host: Rabbit
Source: Human
Source: Human
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Clock. The immunogen shows no significant sequence homology with dPER or other known proteins. Species Reactivity: Human, the immungen sequence is 90% homologous with mouse.
Purity/Purification
Purified by affinity chromatography.
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.02% sodium merthiolate, 40% glycerol.
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.02% sodium merthiolate, 40% glycerol.
Concentration
~1mg/ml (varies by lot)
Sequence Length
846
Applicable Applications for anti-Clock antibody
ELISA, Western Blot
Application Notes
Western blot: 1-10ug/ml using ECL. Immunohistochemistry: not tested. It is recommended that the antibody be tried at 2-20ug/ml. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide per well.
Immunogen
A 20 amino acid peptide near the C-terminus of human Clock (1).
Preparation and Storage
-20 degree C
Related Product Information for anti-Clock antibody
CLOCK, a basic helix-loop-helix (bHLH)/PAS protein, is an important factor in the molecular clock mechanism. Mutations in this protein lead to abnormal circadian behavior and defective transcriptional activity. CLOCK has been shown to interact strongly with other bHLH-PAS proteins such as MOP3, a BMAL1 isoform.
Product Categories/Family for anti-Clock antibody
References
• 1) Antoch, M.P. et al (1997) Cell 89:655-667; King, D.P. et al., (1997) Cell 89:641-653.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
95,304 Da
NCBI Official Full Name
CLOCK
NCBI Official Synonym Full Names
clock homolog (mouse)
NCBI Official Symbol
CLOCK
NCBI Official Synonym Symbols
KAT13D; bHLHe8; KIAA0334
NCBI Protein Information
circadian locomoter output cycles protein kaput; OTTHUMP00000128334; OTTHUMP00000196798; OTTHUMP00000218844; class E basic helix-loop-helix protein 8; circadian locomoter output cycles kaput protein
UniProt Protein Name
Circadian locomoter output cycles protein kaput
Protein Family
UniProt Gene Name
CLOCK
UniProt Synonym Gene Names
BHLHE8; KIAA0334
UniProt Entry Name
CLOCK_HUMAN
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Product Notes
The Clock clock (Catalog #AAA618324) is an Antibody produced from Host: Rabbit Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti - Clock reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Clock can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Western blot: 1-10ug/ml using ECL. Immunohistochemistry: not tested. It is recommended that the antibody be tried at 2-20ug/ml. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide per well. Researchers should empirically determine the suitability of the Clock clock for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Clock, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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