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Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded Ca922 xenograft using CLIC3 antibody at a dilution of 1:100)

Rabbit CLIC3 Polyclonal Antibody | anti-CLIC3 antibody

CLIC3 Antibody

Applications
Immunohistochemistry, Western Blot
Purity
Antigen-Affinity Chromatography
Synonyms
CLIC3; Polyclonal Antibody; CLIC3 Antibody; Affinity Purified Rabbit Polyclonal CLIC3 Antibody; Polyclonal CLIC3 antibody; Anti-CLIC3 antibody; chloride intracellular channel protein 3 antibody; CLIC 3 antibody; CLIC 3; CLIC-3 antibody; chloride intracellular channel 3 antibody; CLIC3 antibody; CLIC-3; anti-CLIC3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen-Affinity Chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.74 mg/ml (varies by lot)
Sequence Length
236
Applicable Applications for anti-CLIC3 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:500
WB: 1:500-1:3000
Immunogen
CLIC3 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 236 of CLIC3
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemical staining of paraffin-embedded Ca922 xenograft using CLIC3 antibody at a dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded Ca922 xenograft using CLIC3 antibody at a dilution of 1:100)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A:HeLa S3) using a 12% SDS PAGE gel and CLIC3 antibody at a dilution of 1:500)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A:HeLa S3) using a 12% SDS PAGE gel and CLIC3 antibody at a dilution of 1:500)

Immunohistochemistry (IHC)

(Immunohistochemical staining of paraffin-embedded T(IV)(lung CA) using CLIC3 antibody at a dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded T(IV)(lung CA) using CLIC3 antibody at a dilution of 1:100)
Related Product Information for anti-CLIC3 antibody
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
Product Categories/Family for anti-CLIC3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27 kDa
NCBI Official Full Name
chloride intracellular channel protein 3
UniProt Protein Name
Chloride intracellular channel protein 3
UniProt Gene Name
CLIC3
UniProt Entry Name
CLIC3_HUMAN

Uniprot Description

CLIC3: Can insert into membranes and form chloride ion channels. May participate in cellular growth control. Belongs to the chloride channel CLIC family.

Protein type: Membrane protein, integral; Channel, chloride

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; chloride channel activity; voltage-gated ion channel activity

Biological Process: chloride transport; signal transduction

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Product Notes

The CLIC3 clic3 (Catalog #AAA5311948) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CLIC3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:500 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the CLIC3 clic3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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