Goat CLEC16A Polyclonal Antibody | anti-CLEC16A antibody
Goat anti-CLEC16A Antibody
Gene Names
CLEC16A; Gop-1; KIAA0350
Reactivity
Expected from sequence similarity: Human, Mouse, Rat
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
CLEC16A; Polyclonal Antibody; Goat anti-CLEC16A Antibody; Goat Anti-CLEC16A (aa1040-53) Antibody; C-type lectin domain family 16; member A; Gop-1; KIAA0350; MGC111457; CLEC16A antibody; member A antibody; Gop-1 antibody; KIAA0350 antibody; MGC111457 antibody; anti-CLEC16A antibody
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
SLENQDKGGERP
Sequence Length
1053
Applicable Applications for anti-CLEC16A antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments gave an approx 70kDa band in rat testis lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to XP_213209.4 predicted in Rat and 118kDa in Human NP_056041.1. The 70kDa band was successfully blocked by incubation with the immunizing peptide.
Western Blot: Preliminary experiments gave an approx 70kDa band in rat testis lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to XP_213209.4 predicted in Rat and 118kDa in Human NP_056041.1. The 70kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence C-SLENQDKGGERP, from the internal region of the protein sequence according to NP_056041.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,283 Da
NCBI Official Full Name
protein CLEC16A isoform 1
NCBI Official Synonym Full Names
C-type lectin domain family 16 member A
NCBI Official Symbol
CLEC16A
NCBI Official Synonym Symbols
Gop-1; KIAA0350
NCBI Protein Information
protein CLEC16A
UniProt Protein Name
Protein CLEC16A
Protein Family
UniProt Gene Name
CLEC16A
UniProt Entry Name
CL16A_HUMAN
NCBI Description
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
CLEC16A: Insulin-dependent diabetes mellitus is significantly associated with variation within a 233-kb linkage disequilibrium block on chromosome 16p13 that includes KIAA0350. Three common non-coding variants of KIAA0350 in strong linkage disequilibrium reach genome-wide significance for association with the disease (PubMed:17632545). Belongs to the CLEC16A/gop-1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component: endosome membrane; lysosomal membrane
Biological Process: autophagy
Research Articles on CLEC16A
Similar Products
Product Notes
The CLEC16A clec16a (Catalog #AAA421561) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-CLEC16A Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC16A can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments gave an approx 70kDa band in rat testis lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to XP_213209.4 predicted in Rat and 118kDa in Human NP_056041.1. The 70kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the CLEC16A clec16a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SLENQDKGGE RP. It is sometimes possible for the material contained within the vial of "CLEC16A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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