Rabbit anti-Mouse, Rat CLCN3 Polyclonal Antibody | anti-CLCN3 antibody
CLCN3 Rabbit pAb
Gene Names
CLCN3; CLC3; ClC-3
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
CLCN3; Polyclonal Antibody; CLCN3 Rabbit pAb; CLC3; ClC-3; anti-CLCN3 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, pH7.3.
Applicable Applications for anti-CLCN3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide of human CLCN3.
Cellular Location
Cytoplasmic vesicle, Early endosome membrane, Golgi apparatus membrane, Late endosome membrane, Membrane, Multi-pass membrane protein, Multi-pass membrane protein, secretory vesicle membrane
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Related Product Information for anti-CLCN3 antibody
Background: This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
818
NCBI Official Full Name
H(+)/Cl(-) exchange transporter 3
NCBI Official Synonym Full Names
chloride channel, voltage-sensitive 3
NCBI Official Symbol
CLCN3
NCBI Official Synonym Symbols
CLC3; ClC-3
NCBI Protein Information
H(+)/Cl(-) exchange transporter 3; H(+)/Cl(-) exchange transporter 3; chloride channel 3; chloride channel protein 3; chloride transporter ClC-3
UniProt Protein Name
H(+)/Cl(-) exchange transporter 3
Protein Family
UniProt Gene Name
CLCN3
UniProt Synonym Gene Names
ClC-3
UniProt Entry Name
CLCN3_HUMAN
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Product Notes
The CLCN3 clcn3 (Catalog #AAA9142773) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLCN3 Rabbit pAb reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLCN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CLCN3 clcn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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