Western Blot (WB)
(Western blot analysis of CLCN2 using K562 whole cell lysates)
Rabbit CLCN2 Polyclonal Antibody | anti-CLCN2 antibody
CLCN2 Antibody
Gene Names
CLCN2; CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; CIC-2; EGI11; HALD2; LKPAT; clC-2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CLCN2; Polyclonal Antibody; CLCN2 Antibody; Chloride Channel 2; Chloride channel protein 2; Chloride channel; voltage sensitive 2; CIC 2; CIC2; ClC-2; CLC2; Clcn2; CLCN2_HUMAN; ECA2; ECA3; EG13; EGI11; EGMA; EJM6; EJM8; PKA-activated chloride channel; anti-CLCN2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CLCN2 antibody detects endogenous levels of total CLCN2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
881
Applicable Applications for anti-CLCN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human CLCN2
Subcellular Location
Membrane.
Tissue Specificity
Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells.
Predicted Cross Reactivity
Pig, Bovine, Horse, Rabbit, Dog, Xenopus
Similarity
Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Xenopus (83%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of CLCN2 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis of CLCN2 using K562 whole cell lysates)
Related Product Information for anti-CLCN2 antibody
Function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
Post-translational Modifications: Phosphorylated. Activated by dephosphorylation.
Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
Post-translational Modifications: Phosphorylated. Activated by dephosphorylation.
Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 98 kDa
Predicted: 99 kDa
Predicted: 99 kDa
NCBI Official Full Name
chloride channel protein 2 isoform 2
NCBI Official Synonym Full Names
chloride voltage-gated channel 2
NCBI Official Symbol
CLCN2
NCBI Official Synonym Symbols
CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; CIC-2; EGI11; HALD2; LKPAT; clC-2
NCBI Protein Information
chloride channel protein 2
UniProt Protein Name
Chloride channel protein 2
Protein Family
UniProt Gene Name
CLCN2
UniProt Synonym Gene Names
ClC-2
NCBI Description
This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Uniprot Description
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
Research Articles on CLCN2
Similar Products
Product Notes
The CLCN2 clcn2 (Catalog #AAA9609692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLCN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLCN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the CLCN2 clcn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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