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Sequence Information ()

Placenta Growth Factor (PLGF) Protein | PLGF protein

Eukaryotic Placenta Growth Factor (PLGF)

Gene Names
Pgf; PIGF; Plgf; AI854365
Applications
SDS-Page, Western Blot
Purity
>95%
Synonyms
Placenta Growth Factor (PLGF); Eukaryotic Placenta Growth Factor (PLGF); Placenta Growth Factor; PlGF2; PGF; PGFL; Placental Growth Factor-Like; Vascular Endothelial Growth Factor-Related Protein; PLGF protein
Ordering
For Research Use Only!
Host
293F cells
Purity/Purification
>95%
Form/Format
Freeze-dried powder
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Sequence
Val19~Pro158
Applicable Applications for PLGF protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Eukaryotic expression
Species
Mouse
Tag
N-terminal His Tag
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Isoelectric Point
7.4
Subcellular Location
Secreted
Usage
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

()

Sequence Information ()

SDS-Page

(Figure. SDS-PAGE)

SDS-Page (Figure. SDS-PAGE)
Product Categories/Family for PLGF protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,876 Da
NCBI Official Full Name
placenta growth factor isoform 1
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
Pgf
NCBI Official Synonym Symbols
PIGF; Plgf; AI854365
NCBI Protein Information
placenta growth factor
UniProt Protein Name
Placenta growth factor
Protein Family
UniProt Gene Name
Pgf
UniProt Synonym Gene Names
Plgf; PlGF
UniProt Entry Name
PLGF_MOUSE

Uniprot Description

PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region; extracellular space

Molecular Function: growth factor activity; protein heterodimerization activity; protein homodimerization activity; vascular endothelial growth factor receptor binding

Biological Process: angiogenesis; induction of positive chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; response to hypoxia; sprouting angiogenesis; ureteric bud branching; vascular endothelial growth factor receptor signaling pathway

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Product Notes

The PLGF pgf (Catalog #AAA2124269) is a Protein produced from 293F cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Placenta Growth Factor (PLGF) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the PLGF pgf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Val19~Pro1 58. It is sometimes possible for the material contained within the vial of "Placenta Growth Factor (PLGF), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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