Rabbit anti-Human CIZ1 Polyclonal Antibody | anti-CIZ1 antibody

CIZ1 Antibody

Cat. Num. AAA9400698

• Gene Names: CIZ1; NP94; LSFR1; ZNF356
• Reactivity: Human
• Applications: Western Blot
• Purity: Antigen affinity purification.
• Synonyms: CIZ1; Polyclonal Antibody; CIZ1 Antibody; NP94; LSFR1; ZNF356; anti-CIZ1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total CIZ1 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.4 mg/ml (varies by lot)
• Sequence Length: 842

• Applicable Applications for anti-CIZ1 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:200-1:1000
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human CDKN1A interacting zinc finger protein 1
• Target Name: CIZ1
• Preparation and Storage: Store at -20 degree C

Testing Data

(Gel: 6%SDS-PAGE Lysate: 40ug A549 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)

Related Product Information for anti-CIZ1 antibody

The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-CIZ1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 196115141
• NCBI GeneID: 25792
• NCBI Accession #: NP_001124487.1
• NCBI GenBank Nucleotide #: NM_001131015.1
• UniProt Accession #: Q9ULV3; Q5SYW3; Q5SYW5; Q8WU72; Q9H868; Q9NYM8; Q9UHK4; Q9Y3F9; Q9Y3G0; A8K9J8; B4E131; B7ZAS8
• Molecular Weight: 88,520 Da
• NCBI Official Full Name: cip1-interacting zinc finger protein isoform 2
• NCBI Official Synonym Full Names: CDKN1A interacting zinc finger protein 1
• NCBI Official Symbol: CIZ1
• NCBI Official Synonym Symbols: NP94; LSFR1; ZNF356
• NCBI Protein Information: cip1-interacting zinc finger protein
• UniProt Protein Name: Cip1-interacting zinc finger protein
• Protein Family: Cip1-interacting zinc finger protein
• UniProt Gene Name: CIZ1
• UniProt Synonym Gene Names: LSFR1; NP94; ZNF356
• UniProt Entry Name: CIZ1_HUMAN

NCBI Description

The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

CIZ1: May regulate the subcellular localization of CIP/WAF1. Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: nucleus

Molecular Function: protein binding; nucleic acid binding; zinc ion binding