Rabbit anti-Human, Mouse CHD2 Polyclonal Antibody | anti-CHD2 antibody

CHD2 antibody

Cat. Num. AAA9407170

• Gene Names: CHD2; EEOC
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunofluorescence
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: CHD2; Polyclonal Antibody; CHD2 antibody; EEOC; anti-CHD2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total CHD2 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 501

• Applicable Applications for anti-CHD2 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunofluorescence: 1:50 - 1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human CHD2.
• Target Name: CHD2
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of HeLa cell line, using CHD2 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cell using CHD2 antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-CHD2 antibody

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Product Categories/Family for anti-CHD2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 110611184
• NCBI GeneID: 1106
• NCBI Accession #: NP_001036037.1
• NCBI GenBank Nucleotide #: NM_001042572.2
• UniProt Accession #: O14647; Q96IP5; C6G482
• Molecular Weight: 56,826 Da
• NCBI Official Full Name: chromodomain-helicase-DNA-binding protein 2 isoform 2
• NCBI Official Synonym Full Names: chromodomain helicase DNA binding protein 2
• NCBI Official Symbol: CHD2
• NCBI Official Synonym Symbols: EEOC
• NCBI Protein Information: chromodomain-helicase-DNA-binding protein 2
• UniProt Protein Name: Chromodomain-helicase-DNA-binding protein 2
• Protein Family: Chromodomain-helicase-DNA-binding protein
• UniProt Gene Name: CHD2
• UniProt Synonym Gene Names: CHD-2
• UniProt Entry Name: CHD2_HUMAN

NCBI Description

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CHD-2: Sequence-selective DNA-binding protein. Belongs to the SNF2/RAD54 helicase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.4.12; Helicase; DNA-binding

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: ATP-dependent DNA helicase activity; DNA binding; histone binding; ATP binding

Biological Process: regulation of transcription from RNA polymerase II promoter; muscle development; transcription, DNA-dependent; chromatin modification; response to DNA damage stimulus; DNA duplex unwinding

Disease: Epileptic Encephalopathy, Childhood-onset